Insulin potentiation therapy (IPT) is an intravenous alternative cancer therapy that uses insulin to enhance the efficacy of low-dose chemotherapy. IPT is much gentler than conventional chemotherapy, and doesn’t come with the horrific side effects patients typically have to endure.
The History Of Insulin Potentiation Therapy
Dr. Steven Ayre is the physician we can thank for bringing IPT to the United States in the 1990s. A family of doctors from Mexico, however, were the ones that invented what is now referred to as Insulin potentiation therapy. Dr Ayre worked alongside these doctors, and the result is the therapy that is used today.
Interestingly, IPT is used as a diagnostic tool in conventional medicine. Before a PET scan is performed, the patient is injected with radioactive glucose. Cancer can be detected by viewing cells that rapidly uptake glucose. IPT is backed by sound science and empirical evidence, and is useful for many types of cancer.
What Is Insulin Potentiation Therapy?
The efficacy of IPT lies in its ability to deliver low-dose chemotherapy to cancer cells through the use of insulin. Insulin, a hormone secreted by the pancreas, acts as a potentiate, increasing the effectiveness of chemotherapy.
Insulin does this by activating receptors on the cell membranes of cancer cells. Chemotherapy agents can then easily enter the cell where they can target cancerous cells, and prevent their spread. Every cell in the body has insulin receptors that enable glucose to enter.
Together with oxygen, this is how ATP, or energy, is made. The mechanism behind why IPT works, is the fact that cancer cells have an abundance of insulin receptors, even up to ten times more than do normal cells. When insulin is delivered into the bloodstream, these cell receptors open, ushering in the chemotherapy drugs.
If you’d like to learn more about IPT, “The Kinder, Gentler Cancer Treatment” is a great resource.
Fermentation And Cancer
Cancer cells differ from healthy cells due to their inability to utilize oxygen to produce energy. Because of this inability, cancer cells make energy via glycolysis or fermentation, resulting in their need for copious amounts of glucose to survive.
This is why people with cancer should eliminate sugar from their diets. Not only does glucose feed cancer, it also deprives healthy cells of nutrition, because cancer cells consume the incoming fuel first, leaving little for normal cells. This survival mechanism, along with the abundance in insulin receptors, allows cancer cells to consume more glucose.
More insulin receptors equate to more glucose entering the cell. IPT can effectively target cancer cells due to their increased permeability, and affinity to quickly bind insulin. Healthy cells don’t bind insulin as quickly because they don’t have as many insulin receptors. This is one of the reasons IPT doesn’t harm normal cells.
IPT capitalizes on cancer’s extreme need for sugar to deliver chemo into the cells. Insulin, which is used off-label as an adjunct to increase cell membrane permeability, is a causal factor behind the success of IPT. Although, both insulin and chemotherapy are FDA approved drugs, IPT is still considered an alternative cancer therapy.
“Balance Your Health: Combining Conventional and Natural Medicine” by Richard Sollazzo is another informative resource.
Low Dose Chemotherapy
Insulin exponentially increases the absorption rates of chemotherapy. That is why the term “potentiate” is used to describe this type of therapy. “Potentiate” means to “intensify”or “multiply.” Because of this increased absorption rate, much lower doses of chemo can be used.
With IPT, only 5-10% of the conventional standard chemotherapy dose is delivered. The amount of insulin that is given is equivalent to what the body would secrete following a normal meal. These low doses spare the patient immense suffering, while still delivering the cancer-killing benefits.
Healthy cells are protected from low-dose chemotherapy because their cell membranes are less permeable as a result of having fewer insulin receptors. The more receptors a cell has, the more permeable it becomes. This is why IPT is so effective in attacking cancer.
Insulin also activates an enzyme called delta-9 desaturase. When activated, this enzyme increases cell-membrane permeability by desaturating the fatty acids within the membranes themselves, allowing the chemo drugs to easily enter.
The Therapeutic Window
Before receiving IPT, a patient refrains from eating for up to 12 hours prior to treatment. A small dose of insulin is then administered, saturating the numerous insulin receptors on the membranes of cancer cells. These receptors become saturated within 20-40 minutes. Small doses of chemo are then administered and absorbed by cancer cells.
During this “therapeutic window,” noncancerous cells remain untouched because their receptors have not been saturated. This entire process is halted once the patient resumes eating.
In traditional chemotherapy, large amounts of cytotoxic drugs are used, in order for enough of the drug to be absorbed, to make the treatment effective. Unfortunately, healthy cells are also harmed in this process, and the immune system takes a huge hit.
Because IPT uses lower doses of chemo, treatment can be administered more frequently. This reduces the chances of cancer cells becoming drug-resistant, while furthering the process of apoptosis, or programmed cell death.
Benefits Of Insulin Potentiation Therapy
We’re all familiar with the miserable side effects associated with traditional chemotherapy. Nausea and vomiting, extreme fatigue and hair loss are just a few of the symptoms that are part and parcel of chemotherapy treatment. Quality of life greatly diminishes, and the toxicity of chemo is often a factor in the demise of the patient. In many cases, chemotherapy kills.
Insulin potentiation therapy uses a much gentler approach. The patient receives all the advantages of chemotherapy without experiencing the extreme discomfort so common with high-dose chemo. Another significant benefit is that the immune system is not obliterated.
It can then do its job of defending the body, not only against cancer, but against infectious organisms, toxic chemicals, radiation, and EMFs.
- Lower doses of chemo can be used
- Treatment can be administered more frequently
- DNA damage does not occur
- The immune system is spared
- No side effects are noted
- Drug-resistance is not an issue
- Cachexia, or muscle wasting, is nonexistent
- Apoptosis is stimulated
- Increased cell-membrane permeability
- Can be used for conditions other than cancer
- Increases the potency and absorption of chemotherapy
One potential side effect of IPT is hypoglycemia or low blood sugar. This isn’t an issue, however, if the patient is carefully monitored.
Insulin potentiation therapy is an alternative cancer therapy that uses insulin and low-dose chemotherapy. Insulin, a pancreatic hormone, opens receptors on cancer cells, allowing chemotherapy to enter where it can accomplish its job of killing cancer and preventing its spread.
The mechanism behind how IPT works is based on human biochemistry, and the distinguishing characteristics of cancer cells. It was first brought to the USA in the 1990s, and is now being used successfully in alternative cancer clinics in the United States, Mexico, and Europe. One such clinic is An Oasis of Healing in Arizona.
Have you or a loved one been treated with IPT? Let me know in the comments:)
 CAM Cancer: Insulin potentiation therapy
 Arizona Center For Advanced Medicine: Frequently Asked Questions About IPT-LD
 Research Gate: Insulin Potentiation Therapy in the Treatment of Malignant Neoplastic Diseases: A Three Year Study Christo Damyanov, Gherasimova DM, Avramov LA and Masley IK
 The Nevada Center of Alternative & Anti-Aging Medicine: INSULIN POTENTIATION CANCER THERAPY
 ScienceDirect: Insulin potentiation therapy: A new concept in the management of chronic degenerative disease
Disclaimer: This article is strictly for informational purposes only and is not intended to be medical advice.